Cushing’s Disease in Dogs, Part 1: What It Is and What to Watch For

Veterinarian Fargo ND | Dog Health Fargo ND | Vet Clinic Fargo ND

Cushing’s disease, also known as hyperadrenocorticism, is a condition we see regularly in older dogs at our Fargo vet clinic. It occurs when the body produces too much cortisol, a stress hormone that helps regulate metabolism, immune function, and more. While cortisol is necessary in normal amounts, chronic overproduction can lead to significant health problems over time.

The most common cause of Cushing’s disease in dogs is a benign tumor on the pituitary gland, which overstimulates the adrenal glands. Less commonly, a tumor on the adrenal gland itself may be to blame. Regardless of the source, the result is the same: the body is flooded with excessive cortisol, and subtle signs start to emerge.

One of the first—and most telling—symptoms pet owners often notice is increased thirst and urination. A dog with Cushing’s may begin emptying the water bowl faster than usual and needing to go outside much more frequently, even having accidents in the house. This change is often what prompts owners to schedule a veterinary exam.

Other signs include:

• Increased appetite

• A pot-bellied appearance

• Hair thinning or loss

• Muscle weakness

• Panting

• Lethargy

These symptoms can be mistaken for normal aging, which is why it’s so important to have your veterinarian involved if your dog starts acting "just a little off."

At Two Rivers Veterinary Hospital, we’re here to help you navigate concerns about your dog’s health with accurate diagnostics and compassionate care. If your dog is drinking more water than usual, it may be more than aging—it could be a sign of something treatable.

Stay tuned for Part 2, where we’ll cover how Cushing’s is diagnosed and the treatment options available.